Marcello Malpighi
De formatione pulli in ovo
The formation of the chick in the egg
Transcribed
by Fernando Civardi
translated by Elio Corti
translation reviewed by Roberto Ricciardi
English text reviewed by Elly Vogelaar
September 2010
The
Latin text is drawn from
Marcelli Malpighii Opera omnia
Londini – apud Robertum Scott MDCLXXXVI
but
because of some mistakes contained in it
it has been emended with the following source
Marcelli
Malpighii Opera omnia
Lugduni Batavorum – apud Petrum Vander MDCLXXXVII
The
footnotes mostly come from
Opere scelte di Marcello Malpighi a cura di Luigi Belloni - Torino UTET 1967
The asterisk indicates that the item is present in lexicon
[1]
DE
FORMATIONE PULLI IN OVO. MAGNAE
SOCIETATI REGIAE ANGLICANAE |
THE
FORMATION OF THE CHICK IN THE EGG Marcello
Malpighi very cordially greets |
Solent
in excitandis machinis praevio operis apparatu singulas efformare
partes, ita ut separata prius pateant ea, quae postmodum redigi debent
in compagem. Hoc in Naturae operibus plures eiusdem Mystae, circa
Animalium indaginem soliciti, accidere sperabant. Corporis etenim
implicatam structuram cum difficillimum sit resolvere, disparatas in
primordiis singulorum productiones intueri iuvabat. Sed vereor,
mortalium vitam incertis nimium finibus claudi, et aeque obscurum esse
carcerem, ac metam.
Quare, sicut Mors, monente Tullio[1],
nec ad vivos, nec ad mortuos pertinet; ita quid tale in primaevo Animalium initio
accidere censeo: dum enim ab Ovo
animalium solicite perquirimus productionem, in Ovo ipso iam fere animal miramur excitatum, ita ut irritus
noster labor reddatur: Nam primum ortum non assequuti, emergentem
successive partium manifestationem expectare cogimur. |
When
machines are built, before starting their assemblage it is usual to
make the single components, so that first are separately seen the
pieces that subsequently have to be joined. Quite a lot of initiates
to the mysteries of nature, very interested in investigating the
animals, hoped that this happened in the works of nature. In fact,
being very difficult to disentangle the tangled structure of the body,
it appeared useful to attentively investigate from the beginning the
separate formation of each part. But I fear that the life of the
mortals is comprised within too much uncertain boundaries and that the
beginning and the end are so much dark. Which is why, as Cicero* says,
like the death is not concerning neither to living nor to dead people,
I think that in the same manner something similar happens in the
initial stages of animals' life: in fact, studying with care the
formation of the animals from the egg, in the egg itself we observe
the animal as if it had been created, so that our labour is frustrated.
In fact, not having understood the beginning of the birth, we are
forced to wait for the following appearing of the parts. |
In
hac quidem perquisitione insudarunt quamplures; inter quos immortalis
vester eminet Harveus, cuius
absolutissimae observationes adhuc ita orbem erudiunt, ut meos
praesertim labores veluti supervacaneos refellant. Quoniam tamen,
eodem afferente[2],
latent plerumque veluti in alta
nocte prima naturae stamina, et subtilitate sua non minus ingenii,
quam oculorum aciem eludunt, tamque varia Naturae vis, incerta
quasi maturitate, modo accelerat, modo differt emergentiam foetus;
ideo rudia quaedam Observationum inchoamenta ex incubatorum Ovorum [2]
lustratione, quam adhuc saepius repetendam propono, me Vobis,
Sodales doctissimi, communicare patiemini, ut si Naturae et magnis
vestris Mentibus consona deprehenderitis, subsequentium annorum
curriculo ea iterum confirmem, consimilium mediatione adaugeam,
novisque, prout tenuitati meae sperare competit, auctiora reddam. |
They
are quite a lot of people indeed that devoted themselves with great
care in this search, among whom emerges your immortal Harvey*, whose
perfect observations are still so full of teachings for everyone to
confute above all my labours as being useless. Since nevertheless, as
he himself affirms, "the first sketches of nature are for the
greater part hidden as in a deep night, and with their thinness they
elude the acuteness of the intelligence no less than of the eyes",
and since the so polymorphous strength of nature, almost with
uncertain timeliness, now accelerates and now delays the appearing of
the fetus, therefore very learned Colleagues you will grant me to
communicate you some rough rudiments of observations inferred from the
analysis of brooded eggs, descriptions that I am proposing to repeat
rather often, so that, if you will find them consistent with nature
and your renowned minds, I can again confirm them during the coming
years, to amplify them by using similar finds and to increase them
with new data as far as it is possible to hope from my littleness. |
Inter
partes, quibus Ovum integratur, Cicatricula[3],
seu circularis macula, primum locum obtinet; in huius enim gratiam
reliqua comproducta videntur. Huius igitur mirabilis structura
indaganda sese offert, cuius praecipuas mutationes, et phaenomena
brevibus indicabo. |
Among
the parts composing the egg, the first place is owed to the cicatricle,
or circular patch, since it seems that thanks to it all the other
things are produced. Therefore its marvellous structure, of which I
will shortly point out the principal changes and appearances, is
offering itself to investigation. |
Haec
itaque in foecundo Ovo
perpetuo observatur arcte Vitelli membranae adhaerens inter chalazas[4];
et albumine cooperitur: multiplicatisque vitellis (ut videre potui)
eadem Cicatricula multiplicatur, unde frequenter in unico ovo tres
deprehendi Cicatriculas. |
Then,
in the fertilized egg, this cicatricle is constantly observed, tightly
sticking to the membrane of the yolk, that is set among the chalazas
and is covered by the albumen. In case of several yolks (as I
succeeded in seeing) the cicatricle is manifold, that's why often I
observed three cicatricles in only one egg. |
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Fig.
1. Fig. 2. - In ovis pridie editis, et nondum
incubatis (ut elapso Augusti
mense, magno vigente calore, observabam) Cicatricula magnitudinem
habebat A, hic a me ruditer
delineatam, in cuius centro sacculus cinerei coloris[5],
interdum ovalis B, quandoque
alterius figurae deprehendebatur. Innatabat huiusmodi sacculus seu
folliculus[6]
in colliquamenti C liquore[7],
vitro fuso persimili, qui irregulari quasi fovea[8]
continebatur: Candidus enim solidae substantiae circulus D[9],
aggeris instar, idem colliquamentum ambiebat, cuius exterior portio
fuso et liquido alluebatur humore E.
Subsequebatur parum lata substantia F,
frequenter varie lancinata, et humore G
pariter mergebatur. Alii insuper ampliores circuli H, ab eadem solidiori excitati substantia circumducebantur,
interpositis liquoris alveolis I.
Exteriores praecipue circulos H,
non uno ritu efficit Natura; nec hi perpetuo continua protrahuntur
substantia. In sacculo postea, velut in amnio[10],
dum solis radiis illum objiciebam, inclusum foetum L[11]
animadvertebam, cujus caput[12]
cum appensae carinae[13]
staminibus patenter emergebat: Amnii etenim rara et diaphana
contextura frequenter translucebat, ita ut contentum appareret animal.
Saepius acus acie folliculum aperiebam, ut contentum animal in lucem
prodiret; incassum tamen: ita enim mucosa erant adeoque minima, ut
levi ictu singula lacerarentur. Quare pulli
stamina in ovo praexistere[14],
altioremque originem nacta esse fateri convenit, haud dispari ritu, ac
in Plantarum ovis. |
In
eggs laid the previous day and not yet brooded
(as I was observing in the last month of August, when it was hot) the
cicatricle had the size A (fig. 1) here by me roughly drawn, at whose
centre was perceived a little sack, ash in colour, sometimes oval B
(fig. 2) and which sometimes had a different appearance. Such saccule
or follicle, floated in the liquid of colliquation C, very similar to
molten glass contained in a kind of irregular pit: in fact a candid
circle of solid substance D, as if being a bank, surrounded the
aforesaid colliquation, and its external part was wetted by the liquid
E melted and thawed.
Immediately after, the substance F was coming, not very wide, often
variously indented, and that likewise was soaked in the liquid G.
Furthermore other more wide circles H, derived from the same more
solid substance, were arranged around, with the interposition of
rivulets I of liquid. The nature doesn't make in the same way the
circles H, above all the more external ones, neither they are always
extending with continuous substance. After, while I was exposing it to
the rays of the sun, I perceived the fetus L held in the little sack
as being an amnion, and its head clearly emerged together with the
sketches of the hooked carina. In fact the loose and diaphanous weave
of the amnion often allowed the light to pass, so that the animal,
contained in it, was visible. I rather often was opening the follicle
with the point of a needle so that the animal contained in it came to
the light. Nevertheless uselessly: in fact the structures were so
sticky and so much little that all of them were tearing at the
slightest trauma. That's why it is worthwhile to admit that the
sketches of the chick are pre-existing in the egg and that they had a
more remote origin, not otherwise it is happening in the eggs of the
plants. |
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Fig.
3 - Placebat etiam subventanea ova[15]
lustrando cicatriculam intueri, quae ut plurimum minima erat; et licet
variam sortiretur circumscriptionem, et texturam, frequentius tamen
delineatam A prae se ferebat
effigiem. Non longe a centro globosum candidumque corpus, seu cinereum
B, quasi mola, locabatur;
quod laceratum nullum peculiare exhibebat corpus a se diversum.
Appendices reticulares C
habebat, quarum spatia diversas referebant figuras, non raro ovales,
diaphanoque replebantur colliquamento; denique tota haec moles, Iridis
instar, plurimis circumdabatur circulis. |
Observing
the windy eggs it seemed me correct
to examine also the cicatricle, that for the more was very small; and
even if having variable contours and structure, nevertheless rather
often was showing the appearance reproduced in A (fig. 3). Not far
from the centre a globular and snow-white formation B, or else ash in
colour, was found, almost similar to a vesicle; after being lacerated,
it didn't show some particular structure different from its one. It
had adnexa C arranged as a net whose spaces had a variable appearance,
not rarely oval, and they were full of a diaphanous fluid liquid;
finally this whole mass was surrounded by a lot of concentric circles
as the rainbow. |
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Fig.
4. - In incubatis autem
Gallinae ovis sub Indica vel nostrate gallina, summo vigente aestu,
tales attingebam mutationes: et primo immediate [3]
post sex incubatus
horas, Cicatricula huius erat magnitudinis A;
in cuius centro aderat Amnion, scilicet B,
candido solidoque circumvallatum aggere C,
quod colliquamenti liquore fusco replebatur. In
medio, pulli carina D una
cum capite innatabat. Huius inferior portio frequenter disrupto
folliculo E[16] contegebatur. Amplus
subsequebatur circulus F, fasciae instar ambiens, qui tandem umbilicalibus pervadebatur
vasis. Non ubique solidum corpus erat, sed sensim irruente ab
exterioribus rivulis colliquamento solvebatur, collis instar, qui
erumpentibus interluitur et mergitur fontibus. Hoc solidiori circulo
subcandido, parumque lato G ambiebatur, qui rivulis et ipse
intercipiebatur. Interdum alii subsequebantur circuli qui incubationis
progressu frangebantur, vel tandem obliterabantur. |
In
eggs of hen brooded by a turkey hen or by a home hen
at the height of summer - 1671 - I observed the following
changes, and first of all, immediately after
6 hours of incubation, its cicatricle
was large as A (fig. 4). At its centre was present the amnion, or B,
surrounded by a snow-white and solid vallum C, full of a dark liquid
of colliquation. In the centre the carina D of the chick fluctuated
together with the head. Its inferior part was often covered by the
lacerated follicle E. The wide circle F was following, enveloping as a
band, that finally was pervaded by the umbilical vessels. It was not a
solid structure in every point, but was gradually melted by a
penetrating colliquation coming from external rivulets, as a hill
irrigated and submerged by sources gushing with violence. This
structure was surrounded by a more solid circle G, whitish and not
very wide, it too interrupted by rivulets. Sometimes other circles
were following each other, interrupted by the progress of incubation,
or were finally deleted. |
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Fig.
5. - Post horas duodecim incubatus, exaratae partes distinctius patebant in
adaucta cicatricula, magnitudinis A,
quae sursum emergens fere horizontalis erat. Disrupto itaque folliculo
B[17],
foetus C erumpebat insigni capite, et duplici vertebrarum ordine[18],
carinae inchoamenta excitante: Hujusmodi namque candidi orbiculares
sacculi, seu vesiculae, invicem contiguae, deorsum excurrebant,
spinalisque medullae[19]
stamina stipabant; et cerebri[20]
pariter primordia subobscure emergebant. Candidus de more circulus D,
Amnion efformaturus, in exteriori colliquamento E
innatabat. Pars F[21],
quae tandem colliquatur, et umbilicalibus vasculis substernitur,
amplior reddita ex subiecto vitello subluteum referebat colorem, et in
ichorem[22]
fusa ab adveniente colliquamento, quasi rivulis, interrumpebatur: In
his tamen motum aliquem non videbam. Candidus circulus G,
omnia de more continens, subsequebatur. Non semel ulteriorem videbam
latam veluti fasciam H, in
qua reticularem plexum I, spadicei
coloris[23],
deprehendebam, vasorum implicationem aemulantem, cuius spatia
exterioris ambitus arctiora erant et sensim obliterabantur, interiora
autem laxiora. An vero huiusmodi sint Umbilicalia
vasa, quae iam in colliquamenti materia latentia, progressu
temporis aeruginoso ichore, et tandem rubescente sanguine turgeant; an
sinus et alveoli ex fermentato colliquamento viam sibi faciente;
determinare non audeo, cum ex humoris diaphaneitate, et sinuum
angustia, localis motus
imperceptibilis existat. |
After
12 hours of incubation, the described
parts were more distinctly visible in the increased cicatricle, whose
size was corresponding to A (fig. 5), and sticking out upward it was
almost horizontal. Therefore, after having opened the follicle B, the
fetus C emerged from it, endowed with a big head and two rows of
vertebrae forming the sketches of the carina. In reality such white
and round pouches or vesicles, neighbouring each other, stretched
downward and surrounded the sketches of the spinal marrow; and also
the sketches of the brain were emerging in a no very evident way. The
circle D, snow-white as usual, destined to form the amnion, floated in
the more external colliquation E. The part F, that at the end is
liquefying and placing itself under the small umbilical vessels, after
becaming greater, was taking a yellowish colour from the underlying
yolk, and melted into ichor - into liquid - was interrupted as by
rivulets by the tributary colliquation: nevertheless in them I didn't
see any movement. The candid circle G was following, that as usual
enclosed every thing. More
than once I
observed a following formation H ample as a band, in which I perceived
the reticular plexus I of colour of the date - dark red - similar to
an interlacement of vessels, whose spaces in the external area were
more narrow and gradually disappeared, while those more internal were
wider. But I don't dare to establish if these formations are umbilical
vessels which, already latent in the material of colliquation, with
the passing of time are swollen of rust coloured liquid and then of
red blood, or if they are sinuses and rivulets coming from the
fermented colliquation making its way. I don't dare to establish these
hypotheses since, on the basis of the transparency of the humour and
the narrowness of the sinuses, doesn't exist any perceivable local
movement. |
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Fig.
6. - Parum absimilis structura
in incubata cicatricula per horas decem
et octo, ovi apicem horizontaliter tenente, emergebat: Namque
pullus A amplo capite, et
oblonga spina, quae disrupto folliculo B
obtegebatur, in adaucto colliquamento de more mergebatur, superstite
adhuc circulo C. Ambiens
pariter substantia D,
colliquamenti rivulis E,
versus Amnion irruentibus[24],
irrigabatur; nondum tamen sanguinea vasa prodibant, Occurrebat amplior
circulus F, rivulo
interposito G, cuius
continuitas in aliquibus tolli coeperat, et quandoque plures ulterius
circuli addebantur. |
In
the cicatricle incubated for 18 hours,
occupying horizontally the higher part of the egg, a little dissimilar
structure was evident. In fact the chick A (fig. 6) with a big head
and a lengthened spinal column, covered by the lacerated follicle B,
was immersed as usual in the increased colliquation, still persisting
the circle C. Item the substance D placed around was irrigated by
rivulets E of colliquation throwing themselves toward the amnion;
however blood vessels had not yet appeared. A wider circle F was
present, with the interposition of the rivulet G, whose continuity in
some eggs had started to stop, and sometimes many further circles were
adding. |
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Fig.
7. - Post diem integrum horarum
24, saepe cicatriculam in summo emergentem, latioremque redditam,
qualem hic delineavi, videbam. Pullus enim A
cum capitis et spinae candido inchoamento, versus inferiora recurvo,
in colliquamento B
sub-oscuro innatabat, et lateri interdum [4]
sinistro folliculi, vel
circuli fragmento G haerebat;
ambiens vero substantia D,
rivulis excavata, extendebatur, et exterior circulus E,
liquore circumdatus, cicatriculae compagem claudebat, ita tamen, ut
derivato ab alveolis exterioribus F
colliquamento versus D
pateret aditus. |
After
a whole day of 24 hours I often saw
that the cicatricle was sticking out at the summit and had become
wider, as I have drawn it here (fig. 7). In fact the chick A, with the
snow-white sketch of head and column bent downward, was floating in
the colliquation B a little bit dark, and sometimes it clung to the
left side of the follicle or of the circle with the portion G; then
the surrounding substance D was extending, dug by rivulets, and the
most external circle E, surrounded by liquid, was closing the
structure of the cicatricle, however in such a way that to the
colliquation F, derived from the external rivulets, a free access
toward D was guaranteed. |
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Fig.
8. - In Vegetiori ovo interdum
singula evidentiora occurrebant; pullus enim in colliquamento A residens oblongiori pollebat carina, eaque recta, quae multis
vertebrarum globosis inchoamentis B[25],
hinc inde a spina locatis, compaginabatur. Alae C[26]
crucis in modum pariter erumpebant, et reliquum capitis, colli, et
thoracis, crassius redditum elongabatur. Tres ampliores vesiculae D, cum producta spinali medulla E[27], usque ad extremum carinae emergebant, et binae pariter orbiculares
globuli F, hinc inde in
capite reponebantur, forte oculorum inchoamenta. Circulus G, olim
colliquamentum ambiens, superiori foetus parti substernebatur.
Umbilicalium vasorum H
surculi primo prodibant, qui contorti e varicosi in colliquamento
mergebantur, nec ipsorum continuata productio adhuc patebat, unde
variae obiiciebantur species; contentus vero humor, interdum
subvitellinus, quandoque rubiginosus erat; huius motum nequaquam
deprehendere valebam. Cordis
motum licet visus fuerim attigisse, non tamen certo affirmare
audebam. |
In
a more vigorous egg sometimes the details were appearing more evident.
In fact the chick located in the colliquation A (fig. 8) was endowed
with a longer and straight carina, which was composed of numerous
spherical sketches B of vertebrae arranged at both sides of the column.
Also the crosswise arranged wings C were sprouting, and the remaining
parts of head, neck and thorax had become thicker and longer. Three
rather great vesicles D, together with the spinal marrow E in
continuity with them, were emerging until the extremity of the carina,
and likewise at each side of the head two spherical globules F were
located, perhaps the sketches of the eyes. The circle G, before
surrounding the colliquation, was below the superior part of the fetus.
For the first time the small branches of the umbilical vessels H
appeared, that, twisted and dilated, were plunged in the colliquation,
but an uninterrupted extension of them was not yet evident, hence
different appearances were noticed. The liquid they contained
sometimes had a colour similar to yolk, other times it had a rust
colour. I was not able at all to catch a movement of it. Although it
seemed me to have noticed a movement of the heart, nevertheless I
didn't dare to affirm it with certainty. |
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Fig.
9. - Absumptis triginta horis, cicatricula taliter configurabatur: In adaucto
amnio A, iacebat pullus B,
in quo novae nondum emerserant partes, praeter capitis appendices, in
aliquibus parum elongatas. Circa amnion perpetuo varicosa umbilicalia
vasa C observabantur, quae
in exteriori limbo D[28]
ampliora, et magis continua, coloris aeruginosi, extendebantur; versus
interiora tamen obscurabatur ipsorum progressus turgente colliquamento:
unde tunc temporis eatenus haec in oculos incurrere dubitabam,
quatenus conglobata reddebantur. Ambientes circuli E,
fusique humoris rivuli F, multiplicabantur,
qui recollectum umbilicalibus, et amnio subministrabant: Non tamen
haec alveolorum ad amussim species obiiciebatur, sed varia quandoque a
Natura promebatur. |
When
30 hours passed, the cicatricle was
shaped as follows. In the amnion A (fig. 9), that had grown, the chick
B was laying, in which new parts not yet sprouted, except the cephalic
appendixes, a little lengthen in some chicks. Around the amnion
umbilical dilated vessels C were always observed, that in the more
external edge D were greater and more continuous, of rust colour.
Nevertheless toward the inner parts their progress was hidden by the
swollen colliquation: therefore then I doubted that such vessels were
visible until they were conglobated. The concentric circles E and the
rivulets F of melted liquid were increasing in number, which supplied
the collected matter to umbilical vessels and amnion. However this
appearance of the canaliculi didn't appear exactly, but sometimes was
shown different by nature. |
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Fig.
10. - Elapso die cum dimidio, parum absimilis occurrebat configuratio. Caput A
solitis vesiculis turgidum, cum alarum inchoamentis B,
et spinali medulla C,
patebat; extremitas carinae D
curvabatur; Umbilicalium vasorum exterior limbus E,
quasi continuato vasculo, adhuc subruginosum continente humorem,
terminabatur, et continuati surculi F,
reticulariter impliciti, versus interiora erant producti. |
When
one day and a half passed, the
appearance was not very dissimilar. The head A (fig. 10) was evident,
swollen by the usual vesicles together with the sketches B of the
wings and spinal marrow C; the extremity of the carina D was bent; the
most external edge E of umbilical vessels was delimited by a small
almost continuous vascular structure still containing an almost rust
coloured liquid, and the little branches F, continuous in structure
and netlike interwoven, were going toward the inner structures. |
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Fig.
11. - Evidentius patuere singula post incubatum horarum triginta octo. Auctior pullus insigni capite A pollebat, in quo tres vesiculae[29]
situabantur, quarum amplior figuram B
prae se ferebat; circum tamen obducebantur involucra C, totum spinae tractum ambientia, quam vertebrarum rotundi
sacculi D de more
componebant. Supra Alarum
exortum, Cordis E structura
primo patebat; quam antea interdum, dubie tamen, mihi detexisse visus
fueram: Vivente enim animali pulsus observabatur; quo cessante fusca
tandem quasi linea designabatur. In colliquamento F
fragmenta circuli G adhuc
supererant. Umbilicalia vasa H
conspicuis surculis varicosis et reticulariter [5]
unitis circum abstabant,
nec adhuc ipsorum productio usque ad Cor emergebat; supernatante enim
colliquamento vel crassiori albumine obscurabantur: Ichor pariter
circum-affundebatur cum innatantibus circulorum solidis fragmentis. |
Each
structure became more evident after an incubation of 38 hours.
The chick, of higher dimensions, was endowed with a big head A
(fig.11) in which three vesicles were located, the greater one showing
the appearance B; nevertheless the wraps C were stretched all around,
surrounding the whole section of the column, composed as usual by the
round vertebral pouches D. Above the origin of the wings appeared for
the first time the structure of the heart E, which sometimes
previously seemed me to identify, even if with some doubts. In fact in
the still alive animal a pulsation was visible, but at its stop a dark
line so to say was drawing. In the colliquation F fragments of the
circle G were still present. The umbilical vessels H were arranged
around with large dilated branches and joined to make a net, but their
lengthening until the heart was not yet noticed; in fact they were
hidden by the above colliquation or denser albumen. Likewise liquid
containing solid floating fragments of circles was spreading all
around. |
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Fig.
12. - Quadraginta elapsis
oris, pullus in colliquamento A degens
pulchrum exhibebat spectaculum; nam crassefacta carina, Caput B curvabatur; Cerebri vesiculae C non ita patentes erant; oculorum D inchoamenta emergebant; Cor E
pulsabat recepto a venis humore, rubiginosi et interdum
xerampelini[30]
coloris: Exterior namque umbilicalium limbus venoso quasi circulo
crassiori F circumducebatur,
qui finibus praecipue G[31]
in cor hiabat: Talis autem ex contento sanguine via, et continentium
structura indicabatur, qualem hic delineatam intuemini. |
When
40 hours passed, the chick, laying in
the colliquation A (fig. 12), was showing a beautiful appearance. In
fact, the carina being increased, the head B was bent; the cerebral
vesicles C were not so apparent; the ocular sketches D were sticking
out; the heart E pulsated, having received from the veins some liquid
rust coloured and sometimes of the colour of a drying leaf of vine: in
fact the external band of the umbilical vessels was surrounded by a
kind of thicker venous circle F, that opened in the heart mainly with
the terminations G. Really such a way, due to the contained blood and
to the appearance of the structures containing it, was put in evidence
as you can see it drawn here. |
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Fig.
13. - Primo itaque motus
Constrictionis ex appulso humore per
venas A[32]
observabatur
evidenter in auriculam B[33];
a qua expressus succus propellebatur per C[34]
in amplum ventriculum dextrum D[35],
qui constrictione media in continuatam appendicem E[36]
protrudebatur, a qua in arteriam Aortam F
patebat aditus; haec autem sursum in caput insignes emittebat ramos[37],
et deorsum in truncum G[38]
se elongabat, qui divisus usque ad extremum carinae producebatur; Fig.
12. -versus tamen mediam regionem umbilicales ramos H[39]
promebat, qui germinatis surculis I
in peripheria absumebantur, excitato reticulari plexu, quem in
relinquorum vasorum sanguineorum extremitate perpetuo miramur.
Consimilis etiam implicatio observabatur circa venosum vas F[40];
quin adhuc vereor, ne sit latum vas, an vero conglomeratus reticularis
plexus venosus, cum frequenter huius vestigia deprehenderim. Pulsantes
itaque successive hasce vesiculas[41]
Verum Cor esse censeo, circa
quas (ut non semel suboscure videbam) musculosae carneae portiones
circumducebantur, nondum opacitatem aut rubedinem sortitae. Quare
motum illum, qui in micante gutta, seu saliente puncto, alias observatus est, nequaquam palpitationem
inclusi sanguinis[42]
esse reor, sed veri cordis motum, pulsum scilicet constrictionis
et dilatationis, qui successive peragitur in debitis ventriculis,
solo loco disparatis, qui tandem uniti, inducta carne, consuetam
adulti cordis excitant fabricam. |
Therefore
it was first of all observed in a well visible way the movement of the
systole thanks to the liquid pushed through the veins A (fig. 13) in
the auricle B, and the liquid it squeezed was pushed through C in the
wide right ventricle D which, after having halved itself, debouched
into the adjacent appendix E, from which the access to the aorta
artery F was opening. Then this was sending forth some big branches in
cranial direction and was lengthening downward in the trunk G that,
after having divided, pushed until the extremity of the carina.
However approximately in the central area it was sending forth the
umbilical branches H (fig. 12), which, after gave origin to the little
branches I, were dispersing in the periphery after having formed a
reticular plexus, as we regularly observe at the extremity of the
other blood vessels. Analogous interweaving was also observed around
the venous vessel F; so that I still fear that it is not a big vessel,
but a venous reticular curled up plexus, since often I observed its
traces. Therefore I believe that these vesicles, subsequently
pulsating, are the true heart, and around them (as many times I saw
not very distinctly) were placed portions of muscular flesh that had
not yet acquired redness and opacity. Then I think that that movement
observed other times in the vibrating drop, or hopping point, is not
at all the palpitation of the contained blood, but the movement of the
true heart, that is, a tightening and dilating pulsation - systole and
diastole - and that it is fulfilled in succession in the ventricles to
this destined, distinguished only by their position, which finally
join up and become covered with flesh, and assume the usual structure
of the adult heart. |
Difficillimum
quidem est sensu ipso confirmare, An Sanguis prior sit exarato Corde?
Licet enim frequentissime fuscus et rubiginosus humor in exterioribus
umbilicalium vasorum finibus appareat nondum videnter emergente Corde;
et speciosum videri possit, Cor fieri excurvato et expanso vase, cui
carneae portiones, veluti manus, exterius aptentur; quoniam tamen tunc
temporis ita mucosa, candida, et lucida sunt omnia, ut sensus
quocunque instrumento munitus nequeat distinctam partium compagem
attingere, et, sicut in Insectis videre est, ultimi senii partes in
primordiis rudimenta habere, ita de Corde adhuc mihi dubitandum
superest: Hoc autem certo sensui patet, Sanguinem seu sanguineam
materiam a primordiis non omnia illa habere, quae in ipso ex post
deprehenduntur. Primo namque colliquamenti species, a rivulis versus
foetum deducti, in vasis patet; mox vi fermentationis sub-vitellinus
et rubiginosus emergit humor, [6]
qui tandem rubicundus evadit; sub postremis hisce naturis, cordis
ministerio in gyrum pellitur. Quare vereri possumus, quod, sicuti in
Sanguinea materia successivae mutationes, inducto colore,
manifestantur; ita pariter cordis structura solo motu evidenter pateat,
et quod quiescens adhuc praeexistat, licet iners, nondum scilicet
firmatis carneis fibris. Hoc vero certum videtur, Ichorem, seu
exaratam materiam, quae postremo rubicunda efficitur, Cordis motum
antecedere; Cor vero suo etiam motu Sanguinis rubificationem. |
Really
it is very difficult to confirm, just basing themselves on the visual
experience, if the blood is pre-existing to the heart we described. In
fact, although very often a dark and rust in colour liquid appears in
the outer extremities of the umbilical vessels when the heart is not
still clearly visible, and although it could seem beautiful that the
heart derives from a bent and expanded vessel, externally to which
pieces of flesh are arranging themselves as being hands; since
nevertheless in such moment everything is so mucous, snow-white and
bright that the eye provided of whatever tool would not be able to
distinctly detect the structure of the parts, and that, as it can be
seen in insects, the parts of the farthest old age have the sketches
in the initial structures; then I am still doubtful about the heart.
In fact to the sight it is certainly clear what follows, that the
blood or haematic material doesn't possess since the beginning all
those things subsequently observed in it. In fact at first in the
vessels something is evident seeming a colliquation, transported by
the rivulets toward the fetus; soon after through the action of the
fermentation a yellowish and rust coloured liquid is highlighting,
finally becoming red, and under this final appearance is pushed around
by cardiac activity. Which is why we can suspect that, as in the
haematic material some following changes are showing themselves
through the assumed colour, so likewise the structure of the heart is
showing itself in a clear way by only the movement, and that it is
pre-existing still quiescent, although inactive, since the fleshy
fibres didn't yet grow stronger. It seems certain what follows, that
the liquid, that is, the described material finally becoming red,
precedes the movement of the heart, as well as that the heart starts
to pulsate before the blood becomes red. |
An
autem Ichor primo emergens sit simplex colliquamentum, an vitalis
liquor, an sanguis inchoatus, cum sensuum ministerio determinari
nequeat, vestris mentibus diiudicandum relinquo; illud unum innuens,
ante Ichoris collectionem, eiusdem motum, et in sanguinis naturam
conversionem, Carinam, cum capitis, cerebri, spinalis medullae, et
alarum[43]
inchoamentis, evidenter patere; et sicut in Plantarum Ovis primo
colligitur colliquamentum, ex quo ab initio Plantae carina sive
truncus cum foliis excitatur; quae singula diversis Vasis, succisque
fermentativis concretis compaginantur: ita in Animalium primaeva et
simultanea productione dubitare fas est; cum suspicari possumus, in
Ovo subesse pullum, cum partium fere omnium conterminis sacculis
innatantem in colliquamento, huiusque naturam nutritivis et
fermentativis succis commixtis integrari, ex quorum suscitata mutua
actione sanguis successive progignitur, partesque olim delineatae
erumpunt, et turgent. Sed tam involuta et latentia sunt haec Naturae
opificia, ut licet sensuum ministerio inquirantur, quoniam tamen circa
minima versantur, facile (me saltem) decipere possint; ideo irritum
prorsus censeo meis coniecturis ea prosequi. Quare redeo ad indagandas
successivas pulli manifestationes. |
But,
being impossible to establish by the employment of the senses if the
liquid at first appearing is a simple colliquation, or a vital liquid,
or a sketch of blood, I leave it to be judged by your minds. I confine
myself to mention that the carina, together with the sketches of head,
brain, spinal marrow and wings, shows itself in evident way before the
liquid gathers, starts to move and turns into blood. And as in the
eggs of the plants at first the colliquation is gathering, from which
since the beginning the carina of the plant originates, that is, the
trunk, together with the leaves, and each structure is composed of
different vessels and thick fermentative juices, it is permissible to
doubt that so happens in the juvenile and simultaneous formation of
the animals, since we can suspect that in the egg the chick hides
itself, floating in the colliquation, with the contiguous pouches of
almost all the parts, and that its nature is renewed by the mixture of
nourishing and fermented juices, thanks to whose mutual stimulation
the blood is subsequently begot, and the parts, for a long time
delineated, erupt and increase. But these laboratories of nature are
so dark and hidden that, as far as they are investigated by using the
senses, being that nevertheless they concern very small things, they
could easily deceive (me at least). Therefore I think undoubtedly
useless to expound them by using my conjectures. Which is why I go
back to the following manifestations of the chick that have to be
investigated. |
Non
in singulis incubatis quacunque tempestate ovis, Cor et appensa
Umbilicalia vasa tam cito manifestabantur: Frequenter enim elapso
altero die emergere solebant; autumno praecipue, et vere, ut saepius
mihi accidebat. Inter observandum, in obscuro etiam conclavi, nunquam
micantem in Corde lucem, etiam
minimam[44],
attingere potui. |
The
heart, and the umbilical vessels suspended from it, didn't show
themselves as much soon in each egg incubated in whichever season: in
fact often they were accustomed to appear when the second day was
passed, especially in autumn and in spring, as rather often it
happened me to observe. Also during the observations in a darkroom,
never I succeeded to see in the heart the slightest sparkling light. |
|
|
Fig.
14. - Binis
superatis diebus,
utplurimum consimilis occurrebat species, qualem delineare mea
manu tentavi; prout nudis etiam oculis obiicitur. Colliquamenti
sacculus, seu amnion A,
copioso fuscoque refertus ichore, Pullum continebat, cuius vesiculae
recurvum caput integrabant; vertebrarum sacculi per longum producti
adhuc patebant; cor B extra
thoracem pendulum, triplici, hocque successivo, pulsu movebatur. Nam
receptus humor, quandoque adhuc rubiginosus, a vena per auriculam in
cordis ventriculos, ab his in arterias, et postremo in umbilicalia
vasa C demandabatur. Saepe
servabam pullum, et exsiccato subiecto vitello, Cor per diem pulsum
non intermittebat. Umbilicalium vasorum limbus D, lato quasi vase terminabatur, cuius quidem crassitiem ex
implicatione reticulari venarum et arteriarum excitari censeo; quod
tamen ulteriori eget inquisitione: Exonerabantur autem venae mediis
extremis finibus E in
auriculam cordis. |
When
2 days passed, mostly was occurring
an appearance similar to that I tried to draw with my hand, so as it
is occurring also to naked eyes. The pouch of the colliquation, that
is the amnion A (fig. 14), full of abundant and dark liquid, contained
the chick, whose vesicles were leaning against the bent head; the
pouches of the vertebrae were also visible, longitudinally placed; the
heart B, hanging outside the thorax, was moving by triplex and
following pulsation. In fact the liquid received from the vein,
sometimes still rust coloured, was sent through the auricle in the
ventricles of the heart and from these in the arteries, and finally in
the umbilical vessels C. Often I conserved the chick and, after the
underlying yolk dried, the heart didn't stop pulsating for one whole
day. The band D of the umbilical vessels was ending as in a wide
vessel whose size in my opinion is provoked by the reticular weaving
of veins and arteries. Nevertheless this needs a further investigation.
Besides the veins were discharging, through the central and terminal
extremities E, in the auricle of the heart. |
|
|
Fig.
15. - Valde solicitus eram
circa primaevam Cordis
apparentem formam, et, quam attingere potui a contento sanguine
delineatam, hic habebitis. [7] Ex quibus patet, sanguinem perpetuo a venis A, a limbo deductis, deferri in auriculam B, a qua, brevi interdum intermedio canali, in dextrum cordis
ventriculum C exprimitur, et
inde in sinistrum D, et
tandem in arterias E, a
quibus in caput F, et
umbilicalia vasa G. |
I
was very attentive about the appearance of the primordial shape of the
heart and you will find it here as I have been able to observe it
outlined by the contained blood. From these images it is evident that
always the blood from the veins A (fig. 15), coming from the band,
passes in the auricle B, from which, through a sometimes brief
intermediary channel, is pushed in the right ventricle C of the heart,
and from here in the left D, and finally in the arteries E, and from
them in the head F and in the umbilical vessels G. |
Circa
exaratos Sanguinis ductus fibrosa diaphanaque musculosae carnis portio
extendebatur, ut subobscure videbam; cuius necessitatem pulsus arguit.
Non semel sanguineos ramos A
a cordis auricula et dextro ventriculo elongatos licet deprehenderim;
adhuc tamen haereo, cum mihi ambigendum occurrerit, productiones esse
subiectorum Umbilicalium vasorum[45]. |
Around
the described blood's ducts a fibrous and diaphanous portion of
muscular flesh was stretching, as I was able to observe in a rather
uncertain way, and the pulsation shows the necessity of it. Even if I
have observed not only once that the blood branches A are departing
from the auricle of the heart and from the right ventricle,
nevertheless I am still doubtful, being happened me a reason for
doubting, if they are ramifications of the underlying umbilical
vessels. |
|
|
Fig.
16. - Post binos
dies, horasque quatuordecim, pullus pariter auctior redditus,
in colliquamento A, curvo capite, pronus iacebat; cerebri vesiculae B,
sanguineis vasis irrigatae, cum oculorum inchoamentis C;
spinalis item medulla per longum exporrecta, vertebris D contenta, observabantur: Externum corporis habitum colliquamenti
E portio, crassior et
obscurior reddita, veluti involucrum[46],
ambiebat: a corde emanabant sanguinea vasa, quae producta versus
medium abdominis, umbilicales arterias F,
et venas G etiam, promebant: Patebant autem venae G, una cum arteriis excurrentes, ex inverso sanguinis motu, et
eandem fere magnitudinem cum arteriis acquisiverant. Extremus
Umbilicalium vasorum limbus H
sanguineis vasculis excitabatur crassefactis, vel saltem reticulariter
implicitis. Placebat, repetitis observationibus, Cordis motum et
figuram rimari, quae talis apparebat; Sanguis partim ab extremo limbo H, et a vena ascendente et descendente I, in auriculam K
eructabatur; haec postea pulsu edito ipsum propellebat in cordis
ventriculum L, qui
constrictione media pallidus efficiebatur, et in proximum ventriculum M,
et tandem in aortam protrudebat, a qua capiti, corporis habitui, et
umbilico communicabatur. |
After
2 days and 14 hours the chick had
become meanwhile greater and was laying prone, with the bent head, in
the colliquation A (fig. 16). The brain vesicles B were visible,
bedewed by blood vessels, together with the ocular sketches C, as well
as the spinal marrow longitudinally arranged and held by the vertebrae
D. The portion of the colliquation E, made denser and darker, was
surrounding, as if being a wrap, the outer part of the body. From the
heart some blood vessels were departing that, going toward the middle
part of the abdomen, sent forth the umbilical arteries F, and also the
veins G. Really the veins G, flowing together with the arteries, were
clearly recognizable from the inverse movement of the blood, and had
acquired almost the same size of the arteries. The most outer band H
of the umbilical vessels was composed of thickened little blood
vessels, or at least woven as a net. I thought advisable to examine,
with repeated observations, the movement and the shape of the heart
appearing as follows: the blood, coming partly from the most external
band H and from the ascending and descending vein I, flowed in the
auricle K; then this, resorting to a pulsation, pushed it in the
ventricle L of the heart, that at half contraction became pale, and
pushed it in the near ventricle M and finally in the aorta, from which
was sent to head, to bodily structure and to navel. |
|
|
Fig.
17. - Transacto triduo, curvo et prono corpore cubantem reperiebam pullum; in
cuius capite A, ultra binos
oculos B, quinque vesiculae C,
humore turgidae, quibus coagmentatur cerebrum: Crurum quoque D
et alarum E inchoamenta
patebant. Vesicularum, cerebrum integrantium, situs et forma talis
erat: In capitis vertice amplior locabatur vesicula[47],
vasculis irrigata, hemisphaerae instar; haec subsequentibus diebus in
binas dividebatur quasi vesiculas[48]:
Unde adhuc haereo, an a principio una an gemina sint vesiculae. In
occipite triangularis quasi vesicula G[49]
addebatur;
sincipitis[50]
vero profundam partem tenebat ovalis vesicula H[51],
cui proxime
locabantur binae vesiculae I[52].
Corporis habitum inducta
caro contegebat, ita ut sanguinis via non ita facile in oculos
incurreret. Oculi B eminebant, et ipsorum pupilla nigra, circularique zona in ima
parte discontinuata[53]
excitabatur; centrum vero crystallinus vitreo contentus tenebat. Prope
eruptionem umbilicalium vesicula K
extra pendebat, sanguineis vasculis irrigata, quem carnosum
ventriculum[54]
censeo. Cordis compages talis erat, qualem hic exhibebo: Naturae enim
mysterium, quod superius innuebam, hac die evidenter patebat; Auricula
namque L sanguinem [8]
a venis M
recipiens, quasi gemino pulsabat motu, veluti binis distincta
ventriculis, et ita in cor sanguis quadam propellebatur via, quae
ulteriori eget indagine. Dexter cordis ventriculus N,
a primordiis notus, de more pulsabat, sinister vero et ipse distincto
motu agitabatur, et latior indies reddebatur, donec consocio unitus
ventriculo pro sinistro manifestaretur; quod subsequentium dierum
inspectionibus magis patebat. |
When
3 days passed, I found the chick
laying with a prone and bent body, and on its head A (fig. 17),
besides the two eyes B, I found 5 vesicles C turgid of liquid, and of
them the brain is made up. Also the sketches of legs D and wings E
were evident. The arrangement and the shape of the vesicles composing
the brain was the following: at the top of the head the greatest
vesicle - F - was located, bedewed by little hemispheric vessels, and
in the following days it was subdividing as in two vesicles; which is
why I am still in doubt if initially the vesicles are only one or two.
In the occipital place an almost triangular vesicle G was added and an
oval vesicle H occupied the deep part of the sinciput, and near H were
situated the two vesicles I. The superimposed flesh was covering the
body surface, so that the way of the blood didn't easily penetrate in
the eyes. The eyes B were bulging, and their pupil lifted in a black
and circular band, interrupted in the inferior part; the crystalline
contained in the vitreous
body occupied the centre. Near the point of coming out of the
umbilical vessels a vesicle K was hanging outside, bedewed by small
blood vessels, I think it to be the muscular stomach. The structure of
the heart was as here I will show: in fact in this day it was clearly
evident the mystery of nature to which I was previously pointing. In
fact the auricle L, receiving blood from the veins M, pulsated almost
with a double movement, as if it was divided in two cavities, and so
the blood was pushed in the heart through a way needing a further
investigation. The right ventricle N of the heart, known since the
beginning, pulsated as usual, while also the left one got excited with
a separate movement and was becoming larger day by day, until, joined
with the other ventricle, it appeared as being the left one; this was
more evident in the observations of the following days. |
|
|
Fig.
18. - Quarta elapsa die manifestior evaserat pullus. Perampli cerebri quinque
vesiculae A adhuc patentes,
magis ad invicem approximabantur, et laceratae ichorem etiam reddebant;
oculi B magis tumidi
expositam servabant figuram; alae D,
et crura E magis elongata,
solidiora reddebantur. Extremitas pariter carinae F
uropygium constitura recurva prominebat; totum corpus adaucta
mucosa carne tegebatur, et vasorum irrigabatur propaginibus; Interior
cavae et aortae progressus condebatur, et funiculus umbilicalium
vasorum G ab abdomine
erumpebat sanguis per arterias propulsus rubicundo saturatoque
inficiebatur colore; qui vero per venas regrediebatur, subluteus erat.
Interius Ichoris[55]
inchoamentum, et candida intestina cum carnoso praecipue ventriculo,
mucosa tamen, manifestabantur. In aliquibus extra thoracem Cor H pendulum situabatur, cuius auriculae I, eidem magis approximatae, sanguinem a venis K
recipiebant, et cordis ventriculis subministrabant: dexter etenim
ventriculus L consuetam sortitus figuram, sinistro M nectebatur, qui latior redditus, retracto aortae principio N,
sensim debitam induebat formam: In aliis vegetioribus ovis, clausa
levi tunica thoracis cavitate, cor intus celabatur, et sinister
ventriculus deorsum pendulus consocio incumbebat ventriculo. |
When
the 4th day passed, the chick was
more evident. The five vesicles A (fig. 18), even more evident, of the
very big brain, were more approaching each other and, when lacerated,
they also sent forth a serosity. The eyes B, more swollen, were
keeping the described appearance. The wings D and the legs E, longer,
were becoming stronger. Item the bent extremity of the carina F was
sticking out, that would have formed the
uropygial gland*. The whole body was covered by mucous
increased flesh and was bedewed by offshoots of the vessels. The inner
way of vena cava and aorta was hidden, and the funicle G of umbilical
vessels was emerging from the abdomen, and the blood pushed through
the arteries was becoming tinged with a red saturated colour, while
that getting back through the veins was yellowish. The sketch of the
liquid - of the liver - and the very white bowels but mucous, above
all with the muscular stomach, were visible more inside. In some
embryos the heart H was pendulous outside the chest and its auricles
I, closer to it, received the blood from the veins K and sent it to
the ventricles of the heart. In fact the right ventricle L, endowed
with the usual appearance, was connecting to the left ventricle M,
which, being become greater, and the initial part of the aorta N
having shortened, was gradually assuming the proper shape. In other
more vigorous eggs, the thoracic cavity having closed through a thin
membrane, the heart was hiding itself inside and the left ventricle,
pendulous outside, was above the ventricle its companion. |
Post
quintam diem in incubato ovo
nil fere novi deprehendebatur praeter maiorem enarratorum
manifestationem. Vasorum umbilicalium extremus limbus, vitellum
ambiens, non excurrente trunco excitabatur, sed ipsorum extremi fines
lateraliter curvati et reticulariter inosculati extremum sortiebantur
terminum. Circa huiusmodi ramos, globuli seu placentulae, ex vitelli
substantia excitatae, hinc inde haerebant. In Vitelli semisphaera,
quae umbilicalibus vasis non tegitur, diversi alveoli, non dissimiles
a cicatricis rivulis, excitabantur. |
After
the 5th day almost nothing new was
observed in the incubated egg, except a greater evidence of the
described things. The most external band of the umbilical vessels
surrounding the yolk was not made by a continuous tract, but their
terminal segments, bent sideways and anastomosed as a net, were ending
at the extreme periphery. Around such branches were sticking at both
sides some globules or small bannocks derived from the substance of
the yolk. In the hemisphere of the yolk, not covered by umbilical
vessels, different small ducts non dissimilar from the rivulets of the
cicatricle were taking shape. |
|
|
Fig.
19. - Sexti
superata die, taliter cubabat pullus in amnio A[56],
insigni pollens capite, cuius amplior vesicula B,
quasi gemina, oblonga excitata scissura, messoriae falci[57]
fortasse locum praebebat, et lacerata nullum reddebat ichorem.
Anteriores binae cerebri vesiculae C,
humiliores redditae, subcrescente carne, parum obscurabantur, quibus
appendebatur rostri inchoamentum: intercepta vero vesicula pene
latitabat; quod et quintae, in occipite locatae, accidebat. Spinalis
medulla, in binas divisa partes, solida per longum carinae
exporrigebatur. Alae, et crura, exporrectis pedibus D,
elongabantur. Abdomen E
clausum, quasi hernia laborans, extra protuberabat. Erumpentia
umbilicalia vasa F partim in tenue albumen G[58],
vitellum et amnion ambiens, partim in vitellum H
producebantur; et arteriae, graciliores redditae, venis ipsis
valde [9] minores erant. In abdomine, Iecoris evidentior structura emergere
incipiebat; reticularis namque compages I
observabatur ex vasis et involucris structuram firmantibus, quibus
miliares glandulae haerebant; et ita sensim spatia replebantur.
Dubitavi interdum, quod, sicuti in testibus et conglobatis glandulis,
exterius, et interius, musculosae carneaeque fibrae areas constituendo
firmant et comprimunt glandularum molem, ita in iecore eaedem reperiri
possint. Iecoris color nondum rubicundus, sed ex candido subfuscus
redditus erat. Cor interius conditum, licet mucosum, binis pulsabat
ventriculis, a quibus lacertosae pendebant auriculae, duplici
excitatae motu, mole adhuc insignes, una cum vasis candidis. Corporis
exterior habitus cute obductus, vasorum reticularibus propaginibus
irrigabatur, et evidentiores reddebantur tumores quidam, seu futurarum
pennarum folliculi. |
When
the 6th day was passed, the chick was
found laying in the amnion A (fig. 19) in this way: it was endowed
with a big head, whose almost doubled greater vesicle B, a lengthened
fissure having taken shape, perhaps offered space to the reaping hook
- the cerebral sickle or great sickle, and when lacerated it didn't
send forth any liquid. The two anterior cerebral vesicles C, having
lowered, were a little bit hidden by the growing flesh, and the sketch
of the beak was hanging on them. The interposed vesicle was almost
hidden, as it was happening also to the fifth vesicle located at the
occiput. The spinal marrow, divided into two parts, was extending
solid along the carina. The wings and the legs were lengthening and
the feet D were enlarged. The abdomen E, closed, was sticking outside
as suffering from hernia. The bursting umbilical vessels F were
distributed partly in the thin albumen G surrounding the yolk and the
amnion, partly in the yolk H; and the arteries, becoming thinner, were
much smaller than the veins themselves. In the abdomen the structure
of the liver started to emerge with greater evidence, and in fact was
observed the reticular structure I, composed of vessels and wraps
strengthening the structure, to which were sticking some small
formations similar to grains of millet; and so the spaces were
gradually filled. Sometimes I doubted that also in the liver the same
muscular and fleshy fibres are available identical to those that, as
in testicles and in compressed glands, outside and inside, by
delimiting some areas, are strengthening and compressing the glandular
mass. The colour of the liver was not reddish yet, but from snow-white
became rather dark. The heart, hidden more inside, although mucous,
pulsated with both ventricles, from which, together with white vessels,
some strong auricles were hanging, stimulated by a double movement and
increased in volume. The outside of the body, covered by skin, was
irrigated by reticular offshoots of vessels, and some protuberances
were becoming more evident, that is, the follicles of the future
feathers. |
|
|
Fig.
20. - Septima terminata
die ita configuratus iacebat pullus: Capite amplo et insigni pollebat,
et cerebrum A etiam extra
eminebat solitis contentum indumentis; quibus laceratis ichor iam
fluidus in solida concreverat filamenta, ventriculorum concamerationes
excitantia. Inter
amplos oculos sensim erumpebat rostrum. Alae et crura cum appensis
pedibus omnimodam sortitae erant configurationem, et venter B
tumidus turgentibus visceribus reddebatur. Umbilicalia vasa foras
erumpentia, per vitellum et albumen producta elongabantur. Conclusum
intra thoracem Cor hanc servabat figuram; geminis sc. ventriculis,
quasi sacculis C contiguis, et in superiori parte unitis, cum superposito
auricularum corpore D
compaginabatur, et bini motus in ventriculis, totidemque in auriculis
succedebant; deorsum enim retractum fistulosum corpus, quod in
continuatas arterias sanguinem a dextro ventriculo receptum pulsu
propellebat, sinistrum ventriculum mole maiorem iam excitaverat: circa
utrosque musculosae spinales fibrae successive obducebantur, quibus
cordis caro compaginabatur, et ambo ventriculi nectebantur, et
ambiebantur. Auriculae et ipsae inaequales et rugosae ex lacertorum
suborta implicatione redditae, quasi novum corculum binis distinctum
cavitatibus constituebant; quod in adultis evidentius patet. Lacerata
cute, carnibus, et mucoso peritoneo, renes oblongi cinerei coloris
apparebant. Iecur ipsum, subluteo interdum suffusum colore, quandoque
cinereo, auctius et solidius reddebatur, et ipsius glandulae non
omnino rotundam et sphaericam referebant figuram, sed oblongiores et
quasi caecales utriculos, ductui hepatico appensos, representabant;
quod in aliquibus glandulosis hepatis racemis et miliaribus glandulis
frequenter observatur. Ventriculus
carnosus, licet adhuc exiguus, candidus erat, solitaque figura
constans; appensa habebat intestina gracilia et alba. |
When
the 7th day passed, the chick was
shaped in the following way. It was standing out for the wide and big
head, and also the brain A (fig. 20) was sticking out on the outside,
held by usual coverings; when they were lacerated the liquid, formerly
fluid, was consolidated in solid filaments forming the cavities of
cerebral ventricles. Among the big eyes the beak was slowly sticking
out. The wings and the legs, with the suspended feet, had reached
their complete conformation and the abdomen B was inflated by the
entrails that were increasing in volume. The umbilical vessels,
pushing their way outward, lengthened by extending themselves through
the yolk and the albumen. The heart, held in the thorax, maintained
the following appearance: that is, it was composed by two ventricles
as being two small contiguous bags and joined in the upper part, with
the overlap of the structure D of the auricles, and two movements
alternated in the ventricles and as many in the auricles. In fact the
tubular structure, that had lowered, with a pulsation pushed the blood
received from the right ventricle in the following arteries, and
already had stimulated the left ventricle that was greater in size.
Around both ventricles were branching in succession some muscular
spine-shaped fibres by which the flesh of the heart was made, and by
which both ventricles were linked and surrounded. The auricles, also
made unequal and wrinkled by the muscular neoformation, almost
constituted a new little heart divided in two cavities, which is more
evident in adult subjects. After the skin, the flesh and the mucous
peritoneum had been lacerated, the lengthened and ash coloured kidneys
were visible. The liver itself, sometimes suffused with yellowish
colour, other times ash coloured, was appearing bigger and more
consistent, and its structures didn't show a quite round and spherical
appearance, but they seemed small cavities rather lengthened, and
almost with blind bottom, hung on the liver duct, a thing often
observed in some clusters of liver structures and in glands structured
as grain of millet. The muscular stomach, although still small, was
white, it showed the usual shape and had hung the delicate and white
intestines. |
|
|
Fig.
21. - Post
octavae diei incubationem
grandior redditus pullus capitis amplitudinem adhuc servabat, quo
aperto, cerebri moles iam solidior erat; nam vesiculae olim disparatae,
nunc unitae, geminas constituebant eminentias, in quibus ventriculi
excitabantur, thalamus pariter seu exortus nervorum opticorum, et
cerebellum cum principio spinalis medullae. Exterior
corporis habitus tuberculis A exasperabatur,
[10] a quibus pennae erumpebant, quae insigniores erant circa dorsum, et
uropygium. Umbilicus B latus
et amplus, ex amnii ambiente tunica, ultra sanguinea vasa, intestinula
(velut in hernia accidit) admittebat. In aperto abdomine Iecur
aeruginosum, in lobos divisum, soliditatem acquisierat; nondum tamen
recollecta observabatur bilis. Cor
de more pulsabat, et lateraliter pulmones candidi emergebant. |
After
the incubation of the 8th day the
chick, that became bigger, still kept a big head, and when opened, the
cerebral mass was by now more compact. In fact the vesicles, before
separated and now united, constituted two twin prominences in which
the ventricles were forming and also the thalamus, that is the origin
of the optic nerves, and the cerebellum with the beginning of the
spinal marrow. The outside of the body was made rough by the bulges A
(fig. 21) from which the feathers came out, that were more evident
around the back and the uropygial gland*. The navel B, wide and ample,
starting from the surrounding amniotic membrane, was housing, besides
the blood vessels, the small intestines (as it happens in a hernia).
In the abdomen, after was opened, the liver, rust in colour,
subdivided into lobes, had acquired solidity, but a collection of bile
was not yet perceived. The heart pulsated as usual and at its sides
the white lungs were standing out. |
|
|
Fig.
22. - Decima
elapsa die, pullus ita cubabat, et ambientibus humoribus nectebatur:
Laceratis membranis, totum ovum circum-vestientibus, et praecipue
crassiori A, quae albuminis fusiorem continebat, corii instar, substantiam,
talis occurrebat species: Pullus B
ita flexo corpore iacebat, innatans in humore C,
propria tunica[59]
contento. Subsequebatur
continuatum vitelli involucrum D[60],
cui appendebatur seu arcte haerebat crassior albuminis portio E.
Singula haec venas F, et
arterias G, umbilicales
recipiebant; lata enim vena H
in tenuioris albuminis tunicam A[61]
deducebatur: Vitelli quoque tunica D
venas et arterias recipiebat, quae non omnino totam ipsius peripheriam
contegebant, sed relicto rotundo spatio[62],
quasi pupilla, qua crassiori albumini nectebatur, exiguos surculorum
fines I in huiusmodi crassum
albumen promebant. Elegantem circa vitellum productionem mirari
licebat, dum evacuata huiusmodi tunica, et, diductis parum ipsius
partibus, supra vitrum extendebatur. Arteriae mole minores erant ipsis
venis, illae vero nequaquam perpetuo vitelli tunicae haerebant, sed
elongatis extremitatibus invicem anastomizatis, caecas quasi
appendices K premebant, quae
a tunica L interius
pendentes in vitelli ichore fusco innatabant, et mergebantur. Arteriis
praecipue copiosi haerebant sacculi M,
qui ambientibus sanguineorum vasorum rivulis firmabantur, et
conglobata vitelli substantia turgebant: singulus utriculus plures
globulos parum depressos continebat. Venarum et arteriarum
umbilicalium rami nequaquam perpetuo unitim excurrebant, sed parum
distantes elongabantur; et caecales arteriarum appendices a venis
transversales surculos recipiebant. Vitelli ichor iam fluidior
redditus subflavus, lentusque erat, et parum mole imminutus videbatur,
multumque defecisse tenuior
albuminis portio deprehendebatur. Pulli exterior habitus, alae praecipue et
uropygium, costulis et musculis firmabantur, et pennis erumpentibus
condecorabantur. Rostrum iam osseum reddebatur; scutum enim pendebat,
cuius angularis portio, centrum occupans, primo candidam et osseam
acquisierat naturam, hancque hexagonum quoddam fusci coloris corpus
continebat, quod et ipsum quasi carnea consimili substantia ambiebatur.
Oculi velamentis, et membrana, qua nicticant, contegebantur. Interius
rubiginoso Iecori appensus pendebat Bilis folliculus, quae caerulea
erat. Ventriculus carnosus una cum elongatis intestinis, rite
configuratis, interdum abdominis cavitatem occupabat, quandoque extra
pendebat; et in ventriculo nil deprehendebatur, in proximo vero
intestino parum bilis stagnabat. |
When
the 10th day passed, the chick was
laying in the following way and was connected with the surrounding
liquids. After the membranes wrapping the whole egg were lacerated,
and above all the thickest A (fig. 22) that, as if made of leather,
contained the more fluid substance of the albumen, the following scene
occurred: the chick B was laying so, with the flexed body, swimming in
the liquid C contained in its own membrane. Underneath was following
the uninterrupted wrap D of the yolk, to which was suspended or
tightly stuck the more dense part E of the albumen. Every one of these
structures received the umbilical veins F and arteries G. In fact a
wide vein H went to end in the membrane A of the more fluid albumen.
Also the membrane D of the yolk received veins and arteries that
however didn't cover entirely its whole periphery, but, leaving a
round space free, almost as a pupil through which was linking to the
more dense albumen, they sent thin endings of little vessels I into
this dense albumen. Around the yolk it was possible to admire an
elegant prolongation of them when, after such membrane had been
emptied, it was stretched above a glass after having divaricated its
parts a little bit. The arteries were of smaller dimensions in
comparison to the veins and they didn't always stick at all to the
membrane of the yolk, but, through lengthened extremities anastomosed
each other, they dug as blind appendixes K that, internally hanging
from the membrane L, were swimming and plunging into the dark liquid
of the yolk. Numerous small sacks M mainly stuck to the arteries, and
they were strengthened by the surrounding rivulets of the blood
vessels and they were bulging because of the accumulated substance of
the yolk. Every wrap contained numerous small round and not very
crushed formations. The branches of the umbilical veins and arteries
didn't flow at all always placed side by side, but remained a little
bit distant, and the blind appendixes of the arteries received some
transversal little vessels from the veins. The liquid of the yolk,
already more fluid, was yellowish and viscous and seemed a little bit
reduced in volume, and it was seen that the thinner portion of the
albumen was strongly decreased. The external appearance of the chick,
above all the wings and the uropygial gland, were consolidated by
small ribs and by muscles and they were embellished by sprouting
feathers. The beak became already bony; in fact a shield was hanging
whose angular part occupying the centre had for the first time
acquired a white and bony appearance, and a hexagonal body dark in
colour contained this part, and also it was surrounded by an almost
fleshy similar substance. The eyes were covered by voiles and by the
nictitating membrane. Inside the rust coloured liver the pouch of the
blue bile was suspended and hanging. The muscular stomach, together
with the bowels that had lengthened and had normal appearance,
sometimes was occupying the cavity of the abdomen, other times was
hanging outside. And in the stomach nothing was found, while in the
following bowel a little bit of bile was stagnant. |
|
|
Fig.
23. - Post
duodecimam diem Pennarum
eruptiones A, dorsi
longitudinem contegebant, et ab extremis pariter alis B
et coxis C erumpebant;
subiectae vero partes quasi implumes erant. In ventre hiatus adhuc aderat,
[11] quo
umbilicalibus D patebat aditus, et quandoque etiam intestinis, et carnoso
ventriculo. Fellea cistis, ab amplo iecore pendens, viridi turgebat
humore, cuius portio in proximum intestinum eructabatur. Intestinulum
a carnoso ventriculo erumpens glandularum[63]
inchoamenta continebat. Pulmonum
pariter compages emergebat, solidefactis costulis, et exterius
extensis musculis. |
After
the 12th day the sprouted feathers A
(fig. 23) were covering the length of the back, and likewise they
sprouted from the end of wings B and thighs C, while the ventral areas
were almost unfledged. In the abdomen was still present an opening
through which the access to the umbilical vessels D was opening and
sometimes also to bowels and muscular stomach. The gall bladder,
hanging from the big liver, was bulging with a green liquid, part of
which was flowing in the nearby intestine. The small intestine
emerging from the muscular stomach contained sketches of glands. Also
the structure of the lungs was evident, the small ribs were
consolidated and externally the muscles were expanded. |
|
|
Fig.
24. - Decima quarta die transacta, iam fere perfectus erat pullus;
pennae A auctiores et
copiosiores eminebant; musculosa caro sub cute turgebat; ossa fere
soliditatem adepta erant; viscera clauso quasi abdomine debitam
circumscriptionem sortiebantur; felleus folliculus subviridis interdum,
quandoque caeruleus, a iecore pendebat, quod pertranseunti umbilicali
venae parum continuabatur: In carnoso ventriculo lac stagnabat, et
proxima intestini portio muco quodam candido replebatur, glandulaeque
copiosae[64]
intra eiusdem substantiam, interserebantur. Cor B
unitis ventriculis compaginabatur, et plures arteriae C[65] tubuli, veluti manus
digiti, olim a corde distantes, iam immediate haerebant; Auriculae D
pariter amplae et impense rubicundae lacertis componebantur
reticulariter implicitis, ita ut areae et spatia diversi coloris
cernerentur. |
When
the 14th day passed, the chick was
already almost completed. The feathers A (fig. 24) were sticking out
greater and more numerous, the muscular flesh was swollen under the
skin, the bones had almost reached the compactness, the entrails, the
abdomen being almost closed, had a right delimitation, the gall
bladder, sometimes greenish sometimes blue, was hanging from the liver,
which was loosely linked with the umbilical vein crossing it. In the
muscular stomach some milky juice was stagnating and the nearby
portion of the bowel was full of a white mucus, and numerous glands
were disseminated in its structure. The heart B was composed by the
ventricles joined each other, and numerous arterial little ducts C, as
fingers of a hand, before distant from the heart, now were tightly
sticking to it. The auricles D, equally wide and intensely red, were
composed by tortuous muscles arranged as net, so that areas and spaces
of different colour were perceived. |
Singula
haec manifestiora magisque firma reddebantur absumptis humoribus,
praecipue utroque albumine, et quasi dimidia vitelli portione, tribus
decorrentibus hebdomadis, quo tempore in lucem proditurus erat pullus,
qui adhuc inclusus pipiens audiebatur. Huius carnosus ventriculus
concreto turgebat succo quasi lacte vel oxygala: superior intestinorum
portio subviridi succo, inferior autem cinereo replebatur humore, et
ab hiante vitelli brevi ductu liquorem recipiebat; extrema vero
intestina cum binis appensis caecis stercoraceo humore inficiebantur.
In abdomine exterius carnosa quaedam labia patentem umbilici hiatum
constituebant, quo admittebatur umbilici portio extra pendens;
funiculus enim quasi nerveus erumpebat, qui sanguineis vasis
spiraliter ductis[66]
circumambiebatur. In corii[67]
cavitate reticularis alborum ductuum plexus quasi gracile omentum
observabatur, mucosa et candida aspersum substantia: Adhuc ambigo, an
eius ope albuminis portio versus foetum deducatur, an vero sit
chalazarum vestigium? Vitelli folliculus ichore semiplenus intra
abdominis claustra custodiebatur. |
Everyone
of these structures was becoming more apparent and more solid after
the disappearance of the liquids, above all of the two albumens and of
almost half the yolk, three weeks being passed, the moment when the
chick was about to come to the light, and still shut up it was heard
peeping. Its muscular stomach was turgid of a dense juice similar to
milk or to sour milk. The upper portion of the bowels was full of
greenish juice, while the lower was full of an ash coloured liquid and
was receiving liquid from the short duct of the yolk that was open.
The terminal portions of the bowels, with both caecal appendixes, were
full of a stercoraceous liquid. Externally, at abdomen level, some
fleshy lips delimited the gaping opening of the navel, through which
was entering the portion of the navel hanging outside: in fact a
funicle similar to a nerve, surrounded by spirally shaped blood
vessels, was coming out. In the cavity of the chorion a reticular
plexus of white ducts was observed similar to a thin omentum sprinkled
with mucous and snow-white substance. I am still uncertain if with its
help a part of the albumen is carried toward the fetus, or rather it
is a residue of the chalazas. The sack of the yolk, half-full of
liquid, was kept and shut up inside the abdomen. |
Postremo,
disponebatur pullus ad exitum; Exterioris namque corticis interdum
ingens portio avulsa videbatur, et parum laceratis subiectis tunicis
pulli rostrum et capitis extremitas erumpebat, non ita tamen ut
ambientem corticem urgere posset; quare a gallina quandoque corticem
aperiri credibile est. |
Finally
the chick was getting ready to go out: in fact sometimes it was seen
that a sizeable part of the outer shell had been removed and being
that the underlying membranes tore a little bit, the beak of the chick
and the extremity of the head were coming out, but not insomuch to be
able to force the surrounding shell, which is why we can believe that
sometimes the shell is opened by the hen. |
|
|
Fig.
25. - In dissecto pullo die quarta ab ortu, vitelli folliculus hanc
servabat figuram A, cum fere ex toto exinanitus brevi ductu B in mediam intestini partem hiaret; unde saepius dubitavi, ab
extremis arteriarum finibus oleosam liquefieri materiam, reliquam
vero, lentum scilicet humorem, recollectum in folliculi cavitate,
velut excrementum in proximum propelli intestinum, cum longe a
ventriculo et tenuibus intestinis eructetur. |
In
the chick sectioned the fourth day from birth,
the sack of the yolk was keeping the appearance A (fig. 25) and,
almost entirely emptied, it was opening in the middle portion of the
bowel through the brief duct B. Therefore I rather often doubted that
the oily material was liquefied by the extreme arterial terminations
and that the remainder material, that is the viscous liquid gathered
in the cavity of the sack, was pushed in the nearby intestine as if
being an excrement, since it was poured far from stomach and small
intestine. |
[12]
Hucusque latentis olim in Cicatrice pulli manifestationem, et ortas
ibidem mutationes, quas in tam obscuro et profundo Naturae penu
inquirebam, et suboscure deprehendebam, in compendium redactas
tumultuarie Vobis exaravi. Abstinui vero ab exponendis reliquis Ovi
partibus, cum passim ab aliis recenseantur; hoc unum innuens, sex esse
tunicas[68],
quarum binae sub cortice immediate locatae sanguineis vasis non
pervaduntur, reliquae vasa recipiunt, et humores varios, albumen
scilicet tenuius et crassius, materiam amnii, in qua natat pullus, et
vitellum continent. Successivam etiam humorum mutationem omisi, cum
fuse apud alios habeatur. Hoc unum addam, tenuius albumen, Chorio
contentum[69],
igni appositum interdum evanescere, praecipue a die decima usque ad
pulli exitum. Idem frequenter accidit contento succo in amnio, qui in
tenello tamen pullo secundum aliquam sui partem concrevit, in adulto
vero, et mox nascituro praecipue, salsus redditus igne evaporat: Humor
pariter in folliculo vitelli coadunatus igne et aere calido concrescit.
Ex his itaque interdum dubitavi, humorem, foetum immediate ambientem,
nutritivas quidem commixtas servare partes, quae ventriculum patenti
oris via subingrediantur, et fortasse extremi habitus laxos subintrent
meatus; sed luculenter insuper fermentativis succis ditari, qui
analogi sint lymphae,
caeterisque humoribus a glandulis praecipue extremi habitus separatis;
unde colliquamentum in cicatrice observatum, et a primordiis pulli
stamina ambiens, hanc eandem sapere naturam saepius dubitando
cogitavi. |
Up
to this point I gave you the summarizing and hasty description of the
chick showing itself, previously hidden in the cicatricle, and of the
changes here arisen, that I was investigating and nebulously observing
in a so dark and immense buttery of foods of nature. In truth I
abstained from exposing the remaining parts of the egg since they are
discussed here and there by other people. I confine myself to mention
only this, that the membranes are six, two of which, situated
immediately under to the shell, are not crossed by blood vessels, the
other ones receive vessels and contain different liquids, that is the
albumen which is the thinner and the thicker, the material of the
amnion - the amniotic fluid - in which the chick swims, and the yolk.
I also omitted the following change of the liquids since among other
authors it is abundantly available. I would add only this: the thinner
albumen, contained in the chorion, when put on the fire sometimes
evaporates, above all starting from the 10th day up to the birth of
the chick. The same thing often happens to the liquid contained in the
amnion, that nevertheless in the youngster chick partially coagulated,
while in the adult chick, and above all in that next to be born, on
the fire becomes salty and evaporates. Item the liquid picked in the
sack of the yolk coagulates at fire and warm air. Therefore on the
basis of these observations sometimes I doubted that the liquid
immediately surrounding the fetus contains some mixed each other
nourishing fractions that would enter the stomach through the
accessible way of the mouth, while perhaps they are penetrating
through the wide meatus of body surface; but that besides the liquid
is abundantly enriched with fermentative juices that would be
analogous to lymph and other liquids secreted by the glands, mainly by
those of body surface. Then repeatedly I thought with some doubts that
this same nature was concerning the colliquation observed in the
cicatricle and surrounding since the earliest stages the sketches of
the chick. |
Pro
exaratorum faciliori intelligentia, ut mos est, addenda esset
Spermaticorum vasorum in Gallo delineatio, et praecipue binarum mammillarum, quae extra
erumpentes, semen fundunt; Gallinae pariter Ovarii cum ani
appendicibus, in quibus glandularum copia extat. Hos autem differo labores, et alias, Vobis ita
consulentibus, ulteriori instituta indagine exponam. |
For
an easier understanding of the described things, the drawing of the
spermatic vessels in the rooster should be added as a rule, and
especially of the two papillae that, when coming out, are pouring the
semen; likewise of hen's ovary with the anal appendixes in which
abundance of glands is found. But I send back these jobs and I will
relate them in another relationship, if you will advise me to do it
after having done further researches. |
Quadrupedum,
et Viviparorum foetuum perquisitionem, cum potiora otia et regias pene
impensas[70]
exigat, iam pene despero. Paucas interim hasce observationum
adumbrationes in tam grandi opere inconcinne collectas, solita, qua favetis, humanitate excipite,
Sodales doctissimi, et
singulorum instituta discussione, vel novos indicate labores, vel perpetuo feriari iubete. Diu valeatis. |
By
now I almost despair to be able to do researches on fetuses of
quadrupeds and viviparous, since they asks more spare time and almost
royal expenses. In the meantime, very learned Colleagues, please
receive with the usual benevolence, by which you sustain me, these few
sketches of observations awkwardly gathered in such a great enterprise;
and after having discussed every single thing, point out me new
researches or enjoin me to rest forever. Do well for a lot of time. |
Dabam
Bononiae, Calendis Februarii 1672. |
I
was delivering in Bologna on February 1st 1672 |
[1] Tusculanae disputationes I, XXXVIII, 91: Itaque non deterret sapientem mors, quae propter incertos casus cotidie imminet, propter brevitatem vitae numquam potest longe abesse, quo minus in omne tempus rei publicae suisque consulat, ut posteritatem ipsam, cuius sensum habiturus non sit, ad se putet pertinere. Quare licet etiam mortalem esse animum iudicantem aeterna moliri non gloriae cupiditate, quam sensurus non sis, sed virtutis, quam necessario gloria, etiamsi tu id non agas, consequatur. Natura vero si se sic habet, ut, quo modo initium nobis rerum omnium ortus noster adferat, sic exitum mors: ut nihil pertinuit ad nos ante ortum, sic nihil post mortem pertinebit. In quo quid potest esse mali, cum mors nec ad vivos pertineat nec ad mortuos? Alteri nulli sunt, alteros non attinget.
[2] Exercitationes de generatione animalium, Londra, 1651, p. 42 (Exerc. 13). – Referenza citata da Luigi Belloni in Opere scelte di Marcello Malpighi (Torino utet 1967).
[3] La cicatricola o cicatricula - piccola cicatrice - è anche detta discoblastula oppure blastoderma. Blastula deriva dal latino scientifico blastula, diminutivo del femminile greco blástë = germoglio, gemma, rampollo, germe, embrione; equivalente è il maschile blastós che ha lo stesso significato. § Cicatricola o cicatricula deriva dal latino tardo cicatricula = piccola cicatrice, diminutivo di cicatrix = cicatrice. Ristretta zona del polo dell'uovo degli uccelli, dove, subito sotto alla membrana vitellina, si trovano il citoplasma e il nucleo. Dalla cicatricola, detta anche discoblastula o disco germinativo, si svilupperà l'embrione.
[4] L'italiano calaza deriva dal greco chálaza, grandine, per l'aspetto particolare dei cordoncini che nell'uovo privato di guscio ricordano due chicchi di grandine; chálaza è derivato a sua volta da una radice indeuropea che significa ghiaccio. Le calaze si dipartono da ciascun polo della cellula uovo e sono dirette secondo l’asse maggiore del guscio. Si tratta di strutture cordoniformi avvolte su se stesse. Verso il polo ottuso si dirige una sola calaza, mentre dall'altro lato ne esistono due tra loro intimamente ritorte. Originano a livello dello strato calazifero e terminano da ciascun lato nella regione dei legamenti dell'albume.
[5]
È il nucleo del Pander, o parte svasata della latebra di vitello bianco
che forma come un letto al disco germinativo. (Luigi Belloni, 1967) §
Christian Heinrich Pander
naturalista ed embriologo nato in Lettonia da genitori tedeschi (Riga 1794
- Pietroburgo 1865). Allievo del medico e naturalista estone Karl Ernst
von Baer (Piep 1792 - Dorpat 1876), dimostrò che lo sviluppo
dell'embrione del pulcino procede attraverso la formazione di tre strati
principali di tessuto, o foglietti germinali (ectoderma, entoderma,
mesoderma), dai quali si formano i diversi organi. Si occupò anche di
geologia e di paleontologia. Gli studi di embriologia sono contenuti in Beiträge zur Entwicklungsgeschichte des Hühnchens im Eye (Contributi
alla storia dell'evoluzione del pollo nell'uovo),
Brönner, Würzburg (1817). § Heinz Christian Pander,
name sometimes given as Christian Heinrich Pander (1794-1865) was a
biologist and embryologist who was born in Riga. In 1817 he received his
doctorate from the University of Würzburg, and spent several years
(1827-1842), performing scientific research from his estate near Riga. In
1820 he took part in a scientific expedition to Bokhara as a naturalist,
and in 1826 became a member of the St. Petersburg Academy of Sciences.
Pander studied the chick embryo and discovered the germ layers (i.e.,
three distinct regions of the embryo that give rise to the specific organ
system). Because of these findings, he is considered by many to be the
founder of embryology. His work in embryology was continued by Karl Ernst
von Baer (1792-1876), who expanded Pander's concept of germ layers to
include all vertebrates. Pander performed important studies in the field
of paleontology, and was the first scientist to describe primitive
creatures known as conodonts. He also did extensive research of fossils
found in the Devonian and Silurian geological strata of the Baltic regions.
(www.worldlingo.com)
[6] Follicolo: dal latino folliculus, diminutivo di follis, sacco, borsa. In anatomia: piccola formazione tondeggiante e cava, che spesso contiene un'altra struttura o un piccolo organo.
[7] Colliquamentum, che di per sé significa sostanza fluidificata, è termine introdotto da William Harvey. Qui il Malpighi indica il blastoderma e la cavità subgerminale sottostante all'area pellucida. (Luigi Belloni, 1967)
[8] La cavità subgerminale. (Luigi Belloni, 1967)
[9] L'area opaca è concepita come una sostanza dotata di una certa consistenza, che subisce una parziale colliquazione, onde si alternano anelli o zone concentriche di colliquamento e di materiale non colliquato. Segue ora la descrizione di questi cerchi alternantisi nell'area vitellina interna ed esterna. (Luigi Belloni, 1967)
[10] L'area pellucida è interpretata come un sacco amniotico. (Luigi Belloni, 1967) § Amnio, amnion o amnios: dal greco amníon, vaso in cui si raccoglieva il sangue delle vittime. Annesso embrionale costituito da un sacco che si sviluppa a spese di una parte dei tessuti formati dall'uovo fecondato (sacco amniotico), contenente – in quantità variabile nei diversi animali e nei vari stadi di sviluppo – un liquido sieroso (liquido amniotico) nel quale è immerso l'embrione ancorato al cordone ombelicale.
[11] Probabilmente, allo stadio della stria primitiva. Il raggiungimento di questo stadio anteriormente all'incubazione è sottolineato dagli autori posteriori, alcuni dei quali hanno invocato a spiegazione il forte calore estivo poco sopra ricordato dal Malpighi. (Luigi Belloni, 1967)
[12] Forse il nodo primitivo. (Luigi Belloni, 1967)
[13] Le strutture assiali del tronco. (Luigi Belloni, 1967) § Carena, dal latino carina (chiglia della nave, guscio della noce), per estensione significa organo animale o vegetale, o parte di esso, che richiama la forma della chiglia di una nave, elemento longitudinale dello scafo, facente parte della struttura del fondo.
[14] Osservazione assai corretta. Infatti l'uovo fecondato comincia a suddividersi fino al momento in cui viene deposto. Nell'uovo fecondato il disco germinativo consta di una massa di 40.000-60.000 cellule derivate dalla divisione ripetuta dello zigote e prende il nome di discoblastula o blastoderma o cicatricola, che appare come un dischetto di colore grigio chiaro del diametro di 4 mm che riposa sulla componente bianca del vitello. Nel caso l’uovo non sia stato fecondato, il disco germinativo è costituito da citoplasma e dal nucleo femminile in degenerazione e il suo diametro è di circa 3,5 mm.
[15] Dette anche ventose o uova del vento, ossia non fertili.
[16] In realtà, il nucleo del Pander. (Luigi Belloni, 1967)
[17] In realtà, il nucleo del Pander. (Luigi Belloni, 1967)
[18] I somiti. (Luigi Belloni, 1967) § Somite, singolare e maschile, deriva dal greco sôma, corpo+-ite. In embriologia, un somite è ciascuno dei segmenti in cui si suddivide la parte dorsale del mesoderma (o epimero), a destra e a sinistra della corda dorsale. I somiti danno origine a elementi che formeranno il derma della cute del tronco (dermatomi), alle masse muscolari (miotomi) e allo scheletro assile (sclerotomi). Ogni somite è connesso al mesoderma insegmentato, posto ventralmente, da un peduncolo (peduncolo del somite). Nella zona caudale dell'embrione il mesoderma è costituito da una massa cellulare dalla quale hanno origine nuovi somiti per cui l'embrione può gradatamente allungarsi. Per alcuni embrioni l'età si indica con il numero dei somiti (per esempio, embrione umano e del pollo).
[19] È incerto cosa abbia osservato qui il Malpighi al posto del midollo spinale, che più avanti egli sembra confondere con la notocorda. (Luigi Belloni, 1967) § Notocorda deriva dal greco nôton = dorso. In embriologia e in zoologia, notocorda equivale a corda dorsale.
[20] Evidentemente, il proencefalo e le vescicole ottiche. (Luigi Belloni, 1967)
[21] Questa parte si riferisce evidentemente all'ampia zona compresa fra D e G. (Luigi Belloni, 1967)
[22] Icòre: dal greco ichør, ichôros, maschile. Secondo la mitologia greca, il purissimo sangue degli dei. Per Aristotele in Historia animalium 586b 32 era il liquido amniotico. Nel linguaggio medico, sia di Ippocrate che di Aristotele, era l'essudato, spesso purulento, secreto da ferite o piaghe infette.
[23] Spadix, in latino, corrisponde al ramo della palma da dattero (Phoenix dactylifera) col suo frutto rosseggiante, per cui l’aggettivo spadiceus significa del colore del dattero, cioè rosso scuro. Il dattero, che anticamente suonava dàttilo, deriva dal latino dactylus, che risale al greco dáktylos, il dito.
[24] E sono quindi concepiti come la fonte del liquido amniotico (in realtà, subgerminale). (Luigi Belloni, 1967)
[25] I somiti. (Luigi Belloni, 1967)
[26] Sono, in realtà, i tronchi onfalo-mesenterici primitivi. (Luigi Belloni, 1967)
[27] Le vescicole cerebrali e il mielencefalo. (Luigi Belloni, 1967)
[28] Il seno terminale. (Luigi Belloni, 1967)
[29] Evidentemente, il proencefalo, il mesencefalo e il metencefalo. (Luigi Belloni, 1967)
[30] Xerampelinus deriva dal greco xërampélinos, da xërós = secco e ámpelos = vite, quindi un colore che richiama quello di una foglia di vite che sta seccando.
[31] Vene vitelline anteriori. (Luigi Belloni, 1967)
[32] Vene vitelline anteriori. (Luigi Belloni, 1967)
[33] L'atrio indiviso. (Luigi Belloni, 1967)
[34] Il canale auricolare. (Luigi Belloni, 1967)
[35] La cavità ventricolare indivisa. (Luigi Belloni, 1967)
[36] Il bulbo cardiaco. (Luigi Belloni, 1967)
[37] Gli archi aortici. (Luigi Belloni, 1967)
[38] L'aorta dorsale. (Luigi Belloni, 1967)
[39] Le arterie onfalo-mesenteriche. (Luigi Belloni, 1967)
[40] Il seno terminale. (Luigi Belloni, 1967)
[41] Analoga successione di cuoricini aveva già osservato il Malpighi nel De bombyce (1669). (Luigi Belloni, 1967)
[42] Come ammetteva invece Harvey. (Luigi Belloni, 1967)
[43] I vasi onfalo-mesenterici. (Luigi Belloni, 1967)
[44] Il Malpighi nega, quindi, la luminosità del punctum saliens (in micante gutta, seu saliente puncto – pagina 5), la minima ignis scintillula descritta da Harvey (cfr. Adelmann, p. 958, nota 1). (Luigi Belloni, 1967)
[45] Quali in realtà sono. (Luigi Belloni, 1967)
[46] Forse la plica cefalica dell'amnio. (Luigi Belloni, 1967)
[47] Il mesencefalo. (Luigi Belloni, 1967)
[48] I lobi ottici. (Luigi Belloni, 1967)
[49] Il metencefalo. (Luigi Belloni, 1967)
[50] Il sincipite è la parte più elevata del cranio.
[51] Il parencefalo. (Luigi Belloni, 1967)
[52] Gli emisferi cerebrali. (Luigi Belloni, 1967)
[53] Per la presenza della fessura coroidea. (Luigi Belloni, 1967)
[54] È in realtà l'allantoide. (Luigi Belloni, 1967) § Allantoide: dal greco allantoeidës, che ha la forma di salsiccia, essendo allâs la salsiccia, il sanguinaccio. In embriologia, uno degli annessi fetali che, negli animali amniotici, ha funzione respiratoria, nutritizia ed escretoria per l'embrione.
[55] L'abbozzo del fegato. (Luigi Belloni, 1967)
[56] Entra finalmente in scena il vero amnio. (Luigi Belloni, 1967)
[57] In anatomia cerebrale umana esistono due falci: la falce cerebellare o piccola falce, prolungamento verticale e mediano della dura madre, che separa i due emisferi del cervelletto; la falce cerebrale o grande falce, il setto meningeo mediano e verticale che si insinua nella scissura interemisferica.
[58] L'allantoide (allantocorio). (Luigi Belloni, 1967)
[59] L'amnio. (Luigi Belloni, 1967)
[60] Il sacco vitellino. (Luigi Belloni, 1967)
[61] L'allantocorio. (Luigi Belloni, 1967)
[62] Il c.d. ombelico ombelicale o vitellino (tra il sacco vitellino e il sacco dell'albume). (Luigi Belloni, 1967)
[63] Il Malpighi allude verosimilmente al prestomaco con gli abbozzi delle ghiandole che descriverà diffusamente nel trattato Sulla struttura delle ghiandole conglobate e parti affini. (Luigi Belloni, 1967)
[64] Il Malpighi allude verosimilmente al prestomaco con gli abbozzi delle ghiandole che descriverà diffusamente nel trattato Sulla struttura delle ghiandole conglobate e parti affini. (Luigi Belloni, 1967)
[65] Da sin. a d. nella figura: il tronco aortico, le due arterie anonime e il tronco polmonare. (Luigi Belloni, 1967)
[66] Forse il peduncolo allantoideo coi rimanenti vasi sanguigni dell'allantoide. (Luigi Belloni, 1967) § Allantoide: dal greco allantoeidës, che ha la forma di salsiccia, essendo allâs la salsiccia, il sanguinaccio. In embriologia, uno degli annessi fetali che, negli animali amniotici, ha funzione respiratoria, nutritizia ed escretoria per l'embrione.
[67] Còrion: dal greco chórion = membrana, membrana che avvolge il feto, membrana dell'uovo. Annesso embrionale degli Amnioti, costituito da una membrana che, avvolgendo l'embrione (racchiuso nell'amnios), l'allantoide e il sacco del tuorlo, delimita con la propria parete anche la cavità del celoma extraembrionario. Nei rettili, negli uccelli e nei mammiferi lo sviluppo embrionale è caratterizzato da aree extra-embrionali dette annessi embrionali. Si tratta di amnios, corion, sacco vitellino, allantoide e placenta, quest'ultima presente nei soli mammiferi placentati. § Trattasi, in realtà, della cavità allantoidea contenente frustoli di urina solida (masse di urati). (Luigi Belloni, 1967)
[68] Ossia: la testacea esterna, la testacea interna, l'allantocorio, il sacco dell'albume, l'amnio, e il sacco vitellino. (Luigi Belloni, 1967)
[69] Ossia, l'allantocorio. (Luigi Belloni, 1967)
[70] Echeggia qui l'inno di Harvey al mecenatismo del re Carlo I. Si veda anche la Lettera a J. Spon. (Luigi Belloni, 1967)